Anne-Marie  Chang 

 Anne-Marie Chang

Assistant Professor of Biobehavioral Health

Contact Information

120 Biobehavioral Health Building
University Park PA 16802

814-863-5226

amchang@psu.edu

sleep.med.harvard.edu/people/faculty/179/Anne-Marie+Chang+PhD

Research Interests

Genetic analysis of sleep and circadian rhythms, and interactions that influence cardio-metabolic function in humans; examination of environmental effects on sleep physiology, circadian rhythms, and neurobehavioral and cognitive performance.

Education

Ph.D., Northwestern University, 2003

Professional Experience

Selected Publications

Chang AM, Aeschbach D, Duffy JF, Czeisler CA.
Evening use of light-emitting eReaders negatively affects sleep, circadian timing, and next-morning alertness.
Proc Natl Acad Sci U S A. 2014. 

Anderson C, Chang AM, Sullivan JP, Ronda JM, Czeisler CA. Assessment of drowsiness based on ocular parameters detected by infrared reflectance oculography.
J Clin Sleep Med. 2013 Sep;9(9):907-20, 920A-920B. doi:10.5664/jcsm.2992.

Chang AM, Scheer FA, Czeisler CA, Aeschbach D.  Direct effects of light on alertness, vigilance, and the waking electroencephalogram in humans depend onprior light history.
Sleep. 2013 Aug 1;36(8):1239-46. doi:10.5665/sleep.2894.

Lim AS, Chang AM, Shulman JM, Raj T, Chibnik LB, Cain SW, Rothamel K, Benoist C, Myers AJ, Czeisler CA, Buchman AS, Bennett DA, Duffy JF, Saper CB, De Jager PL. A common polymorphism near PER1 and the timing of human behavioral rhythms.
Ann Neurol. 2012 Sep;72(3):324-34. [PMID: 23034908]

Chang AM, Santhi N, St Hilaire M, Gronfier C, Bradstreet DS, Duffy JF, Lockley SW, Kronauer RE, Czeisler CA. Human responses to bright light of different durations.
J Physiol. 2012 Jul 1;590(Pt 13):3103-12. Epub 2012 Apr 23. [PMID: 22526883]

Duffy JF, Cain SW, Chang A-M, Phillips AJK, Munch MY, Gronfier C, Wyatt JK, Dijk D-J, Wright KP, Czeisler CA. Sex difference in intrinsic circadian period in humans.
PNAS 2011 May 2. Epub. [PMCID: PMC3176605]

Duffy JF, Cain SW, Chang A-M, Phillips AJK, Munch MY, Gronfier C, Wyatt JK, Dijk D-J, Wright KP, Czeisler CA. Sex difference in intrinsic circadian period in humans.
PNAS 2011 May 2. Epub. [PMCID: PMC3176605]

Chang A-M, Buch AM, Bradstreet DS, Klements DJ, Duffy JF. Human diurnal preference and circadian rhythmicity are not associated with the Clock 3111T/C gene polymorphism.
Journal of Biological Rhythms 2011;26(3):276-279. [PMID: 21628555]

Chang A-M, Scheer FAJL, Czeisler CA. The human circadian system adapts to prior photic history.
Journal of Physiology (London) 2011;589(5):1095-1102. [PMID: 21224217]

Lee JH, Wang W, Silva EJ, Chang AM, Scheuermaier KD, Cain SW, Duffy JF. Neurobehavioral performance in young adults living on a 28-h day for 6 weeks.
Sleep. 2009 Jul 1;32(7):905-13. [PMID: 19639753]

Chang AM, Reid KJ, Gourineni R, Zee PC. Sleep timing and circadian phase in delayed sleep phase syndrome.
J Biol Rhythms. 2009 Aug;24(4):313-21. [PMID: 19625733]

Vitaterna MH, Ko CH, Chang AM, Buhr ED, Fruechte EM, Schook A, Antoch MP, Turek FW, Takahashi JS. The mouse Clock mutation reduces circadian pacemaker amplitude and enhances efficacy of resetting stimuli and phase-response curve amplitude.
Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9327-32. Epub 2006 Jun 5. [PMID: 16754844]

Reid KJ, Chang AM, Dubocovich ML, Turek FW, Takahashi JS, Zee PC. Familial advanced sleep phase syndrome.
Arch Neurol. 2001 Jul;58(7):1089-94. [PMID: 11448298]

Valentinuzzi VS, Buxton OM, Chang AM, Scarbrough K, Ferrari EA, Takahashi JS, Turek FW. Locomotor response to an open field during C57BL/6J active and inactive phases: differences dependent on conditions of illumination.
Physiol Behav. 2000 May;69(3):269-75. [PMID: 10869592]

King DP, Vitaterna MH, Chang AM, Dove WF, Pinto LH, Turek FW, Takahashi JS. The mouse Clock mutation behaves as an antimorph and maps within the W19H deletion, distal of Kit.
Genetics. 1997 Jul;146(3):1049-60. [PMID: 9215907]

Antoch MP, Song EJ, Chang AM, Vitaterna MH, Zhao Y, Wilsbacher LD, Sangoram AM, King DP, Pinto LH, Takahashi JS. Functional identification of the mouse circadian Clock gene by transgenic BAC rescue.
Cell. 1997 May 16;89(4):655-67. [PMID: 9160756]

Vitaterna MH, King DP, Chang AM, Kornhauser JM, Lowrey PL, McDonald JD, Dove WF, Pinto LH, Turek FW, Takahashi JS. Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior.
Science. 1994 Apr 29;264(5159):719-25. [PMID: 8171325]

Curriculum Vitae

Anne-Marie Chang vitae